Yukinao Kohda Selected Research

Flecainide (Tambocor)

7/2013	SCN5A promoter haplotype affects the therapeutic range for serum flecainide concentration in Asian patients.
11/2012	CYP2D6 genotype affects age-related decline in flecainide clearance: a population pharmacokinetic analysis.
7/2009	Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: involvement of CYP1A2-mediated metabolism.
10/2007	Gender-associated differences in pharmacokinetics and anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia.
11/2006	Effect of CYP2D6 genotype on flecainide pharmacokinetics in Japanese patients with supraventricular tachyarrhythmia.
1/2005	Assessment of serum flecainide trough levels in patients with tachyarrhythmia.
9/2004	Simultaneous determination of serum flecainide and its metabolites by using high performance liquid chromatography.
6/2003	Liquid chromatographic determination of unbound flecainide in therapeutic drug monitoring.
8/2002	High performance liquid chromatography for routine monitoring of serum flecainide.

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Yukinao Kohda Research Topics

Disease

10	Tachycardia (Tachyarrhythmias) 12/2020 - 08/2002
5	Anemia 01/2006 - 08/2002
3	Leukopenia 12/2021 - 11/2016
2	Carcinoma (Carcinomatosis) 10/2017 - 10/2004
2	Pain (Aches) 10/2017 - 12/2005
2	Mania (Manias) 01/2016 - 01/2015
2	Mental Disorders (Mental Disorder) 11/2015 - 12/2006
2	Infections 01/2015 - 10/2004
2	Hepatitis C 01/2013 - 10/2004
2	Body Weight (Weight, Body) 11/2012 - 11/2006
2	Hemolytic Anemia 01/2006 - 10/2004
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2019
1	Deglutition Disorders (Dysphagia) 01/2018
1	Mucositis 10/2017
1	Neutropenia 11/2016
1	Vomiting 01/2016
1	Alopecia (Baldness) 11/2015
1	Bipolar Disorder (Manic Depressive Psychosis) 01/2015
1	Hypotension (Low Blood Pressure) 01/2013
1	Oral Candidiasis (Thrush) 04/2009
1	Autoimmune Diseases (Autoimmune Disease) 04/2009
1	Hypercholesterolemia 04/2009
1	Breast Neoplasms (Breast Cancer) 01/2009
1	Liver Cirrhosis (Hepatic Cirrhosis) 06/2008
1	Schizophrenia (Dementia Praecox) 12/2006
1	Hypokalemia 10/2006
1	Liddle Syndrome 10/2006
1	Hypertension (High Blood Pressure) 10/2006
1	Treatment-Resistant Schizophrenia 04/2006
1	Neuralgia (Stump Neuralgia) 09/2005
1	Tetanus 06/2002

Drug/Important Bio-Agent (IBA)

9	Flecainide (Tambocor)FDA LinkGeneric 07/2013 - 08/2002
5	Pharmaceutical PreparationsIBA 01/2019 - 01/2005
4	Lithium Carbonate (Eskalith)FDA LinkGeneric 12/2021 - 01/2015
3	Antipsychotic Agents (Antipsychotics)IBA 12/2021 - 11/2016
3	Ribavirin (Virazole)FDA LinkGeneric 01/2006 - 04/2004
2	TabletsIBA 01/2019 - 01/2018
2	Analgesics (Analgesic Drugs)IBA 10/2017 - 06/2002
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2009
2	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 07/2009 - 11/2006
2	Rabeprazole (Aciphex)FDA Link 01/2009 - 10/2004
2	Hemoglobins (Hemoglobin)IBA 01/2006 - 04/2004
2	InterferonsIBA 01/2006 - 04/2004
2	Clonidine (ST 155)FDA LinkGeneric 09/2005 - 06/2002
2	Tacrolimus (Prograf)FDA LinkGeneric 02/2005 - 08/2002
1	5-hydroxypropafenoneIBA 12/2020
1	Propafenone (Rythmol)FDA LinkGeneric 12/2020
1	Blood Glucose (Blood Sugar)IBA 01/2019
1	voglibose (Basen)IBA 01/2019
1	xanthan gum (xanthan)FDA LinkGeneric 01/2019
1	Indomethacin (Indometacin)FDA LinkGeneric 10/2017
1	1- (4- chlorobenzoyl)- 3- (2- (1H- imidazol- 1- yl)- 2- oxoethyl)- 5- methoxy- 2- methyl- 1H- indoleIBA 10/2017
1	Oral SpraysIBA 10/2017
1	Aripiprazole (Abilify)FDA Link 01/2017
1	Quetiapine Fumarate (Seroquel)FDA Link 01/2017
1	Adenine FDA LinkGeneric 11/2016
1	Valproic Acid (Depakote)FDA LinkGeneric 11/2015
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2015
1	Cytochrome P-450 CYP1A2 InhibitorsIBA 01/2013
1	GuanosineIBA 01/2013
1	Nucleoside Transport Proteins (Nucleoside Transporter)IBA 01/2013
1	GlucocorticoidsIBA 04/2009
1	Prednisolone (Predate)FDA LinkGeneric 04/2009
1	Omeprazole (Prilosec)FDA LinkGeneric 01/2009
1	Pantoprazole (Protonix)FDA LinkGeneric 01/2009
1	Lansoprazole (Prevacid)FDA LinkGeneric 01/2009
1	tizanidine (Zanaflex)FDA LinkGeneric 06/2008
1	Anti-Arrhythmia AgentsIBA 10/2007
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2006
1	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2006
1	CreatinineIBA 11/2006
1	Glycyrrhizic Acid (Glycyrrhizin)IBA 10/2006
1	shakuyaku-kanzoh-tohIBA 10/2006
1	PotassiumIBA 10/2006
1	shosaiko-to (TJ9)IBA 10/2006
1	Adenosine Triphosphate (ATP)IBA 04/2006
1	Ropivacaine (Naropin)FDA LinkGeneric 12/2005
1	Glutamic Acid (Glutamate)FDA Link 09/2005
1	Amantadine (Aman)FDA LinkGeneric 09/2005
1	Vinblastine (Vinblastine Sulfate)FDA Link 10/2004
1	Proton Pump InhibitorsIBA 10/2004
1	Interferon-alpha (Interferon Alfa)IBA 10/2004
1	ImmunosorbentsIBA 08/2002
1	EnzymesIBA 08/2002
1	Anesthetics (Anesthetic Agents)IBA 06/2002
1	Hypnotics and Sedatives (Sedatives)IBA 06/2002
1	Sevoflurane (Ultane)FDA LinkGeneric 06/2002

Therapy/Procedure

5	Therapeutics 10/2017 - 04/2004
1	Radiotherapy 10/2017
1	Parenteral Nutrition 01/2016
1	Drug Tapering 11/2015
1	Controlled Hypotension 06/2008
1	Punctures 09/2005
1	Liver Transplantation 08/2002
1	Anesthesia 06/2002